iPTMnet Report for O95816 (BAG2)
Protein Information
UniProt AC / UniProt ID | O95816 / BAG2_HUMAN |
Protein Name | BAG family molecular chaperone regulator 2 |
Gene Name | Name: BAG2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95816 |
PRO Name | BAG family molecular chaperone regulator 2 (human) |
Definition | A BAG family molecular chaperone regulator 2 that is encoded in the genome of human. |
Short Label | hBAG2 |
Category | organism-gene |
O95816 (BAG2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | P49137 (MAPKAPK2) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 15271996, 20068231 | |
S31 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S73 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 23186163 | ||
K111 | Acetylation | score1 | PhosphoSitePlus | |||
K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
C162 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K168 | Acetylation | score1 | PhosphoSitePlus | |||
K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
K169 | Acetylation | score1 | PhosphoSitePlus | |||
T176 | O-Glycosylation | score1 | GlyGen | 23301498, 34725712, 34019948, ... | ||
T176 | Phosphorylation | score1 | PhosphoSitePlus | |||
K186 | Acetylation | score1 | PhosphoSitePlus | |||
K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
T201 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S20 | Phosphorylation | P49137 (MAPKAPK2) | score2 | HPRD | 19651622, 15271996, 20068231 | |
S73 | Phosphorylation | score0 | HPRD | 18691976 | ||
S133 | Phosphorylation | score0 | HPRD | 20068231 | ||
S137 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y139 | Phosphorylation | score0 | HPRD | 20068231 | ||
S140 | Phosphorylation | score0 | HPRD | 20068231 | ||
S143 | Phosphorylation | score0 | HPRD | 20068231 | ||
S144 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K123 | T123 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S144 | C144 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K168 | N168 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |