iPTMnet Report for O95793 (STAU1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95793 / STAU1_HUMAN
Protein Name Double-stranded RNA-binding protein Staufen homolog 1
Gene Name Name: STAU1
Synonyms:STAU;
Organism Homo sapiens (Human)

PRO ID PR:O95793
DAG View
PRO Name double-stranded RNA-binding protein Staufen homolog 1 (human)
Definition A double-stranded RNA-binding protein Staufen homolog 1 that is encoded in the genome of human.
Short Label hSTAU1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95793 (STAU1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus
R98 Methylation PhosphoSitePlus
R108 Methylation PhosphoSitePlus   UniProt 24129315
R115 Methylation PhosphoSitePlus   UniProt 24129315
Y116 Phosphorylation PhosphoSitePlus
Y118 Phosphorylation PhosphoSitePlus
K155 Acetylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus   UniProt 23186163
S221 Phosphorylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y281 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
K341 Acetylation PhosphoSitePlus
T362 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K363 Ubiquitination PhosphoSitePlus
K367 Acetylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K399 Ubiquitination PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
Y461 O-Glycosylation GlyGen 25813380
T464 O-Glycosylation GlyGen 25813380
T464 Phosphorylation PhosphoSitePlus
S465 O-Glycosylation GlyGen 25813380
T467 O-Glycosylation GlyGen 25813380
T467 Phosphorylation PhosphoSitePlus
Y495 Phosphorylation PhosphoSitePlus
Y506 Phosphorylation PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S60 Phosphorylation HPRD 20068231
S390 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus
T21 Phosphorylation PhosphoSitePlus
S309 Phosphorylation HPRD 19413330
Site PTM Type PTM Enzyme Score Source PMID
S315 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 F2 Biomuta DOID:4159 / skin cancer [ cosmic ]
S20 A20 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R98 W98 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R115 M115 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
Y118 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K155 T155 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S221 L221 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S309 F309 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S315 F315 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S390 F390 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S465 L465 Biomuta [ cosmic ]