iPTMnet Report for O95785 (WIZ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95785 / WIZ_HUMAN
Protein Name Protein Wiz
Gene Name Name: WIZ
Synonyms:ZNF803;
Organism Homo sapiens (Human)

PRO ID PR:O95785
DAG View
PRO Name protein Wiz (human)
Definition A protein Wiz that is encoded in the genome of human.
Short Label hWIZ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95785 (WIZ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R27 Methylation PhosphoSitePlus
S824 Phosphorylation PhosphoSitePlus
S891 Phosphorylation PhosphoSitePlus
K955 Acetylation PhosphoSitePlus
K967 Methylation PhosphoSitePlus
S968 Phosphorylation PhosphoSitePlus
K975 Methylation PhosphoSitePlus
S982 Phosphorylation PhosphoSitePlus
S983 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 22028470
K988 Sumoylation PhosphoSitePlus
T989 Phosphorylation PhosphoSitePlus
S996 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...19690332, 20068231
T998 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S1006 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...19690332, 20068231
S1010 Phosphorylation PhosphoSitePlus
S1012 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 17287340, 19690332, 20068231
S1017 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 17287340, 19690332, 20068231
S1025 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1064 Phosphorylation PhosphoSitePlus
T1072 Phosphorylation PhosphoSitePlus
S1079 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1106 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1108 Methylation PhosphoSitePlus
K1108 Sumoylation PhosphoSitePlus
K1112 Methylation PhosphoSitePlus
K1112 Sumoylation PhosphoSitePlus
S1121 Phosphorylation PhosphoSitePlus
S1122 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1127 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16565220
S1129 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
S1134 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16565220, ...18669648, 20068231
K1138 Ubiquitination PhosphoSitePlus
K1139 Methylation PhosphoSitePlus
S1146 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1151 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1153 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1155 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1159 Phosphorylation PhosphoSitePlus
K1162 Methylation PhosphoSitePlus   UniProt 18438403
S1171 Phosphorylation PhosphoSitePlus
K1177 Acetylation PhosphoSitePlus
K1177 Sumoylation PhosphoSitePlus
T1213 O-Glycosylation GlyGen 23301498, 33465208
S1218 Phosphorylation PhosphoSitePlus
S1248 Phosphorylation PhosphoSitePlus
S1263 Phosphorylation PhosphoSitePlus   UniProt 20068231
K1282 Sumoylation PhosphoSitePlus
S1309 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1314 Phosphorylation PhosphoSitePlus   UniProt 20068231
K1322 Methylation PhosphoSitePlus
S1335 Phosphorylation PhosphoSitePlus
T1337 Phosphorylation PhosphoSitePlus
T1340 Phosphorylation PhosphoSitePlus
T1347 Phosphorylation PhosphoSitePlus
Y1349 Phosphorylation PhosphoSitePlus
S1352 Phosphorylation PhosphoSitePlus
K1356 Acetylation PhosphoSitePlus
K1356 Methylation PhosphoSitePlus
K1356 Sumoylation PhosphoSitePlus
K1356 Ubiquitination PhosphoSitePlus
R1363 Methylation PhosphoSitePlus
K1370 Sumoylation PhosphoSitePlus
K1372 Sumoylation PhosphoSitePlus
K1382 Methylation PhosphoSitePlus
K1382 Sumoylation PhosphoSitePlus
K1382 Ubiquitination PhosphoSitePlus
K1384 Methylation PhosphoSitePlus
S1393 Phosphorylation PhosphoSitePlus
R1460 Methylation PhosphoSitePlus
K1464 Methylation PhosphoSitePlus
S1480 Phosphorylation PhosphoSitePlus   UniProt 23186163
R1493 Methylation PhosphoSitePlus
S1517 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T1521 Phosphorylation PhosphoSitePlus
K1523 Sumoylation PhosphoSitePlus
K1534 Sumoylation PhosphoSitePlus
K1534 Ubiquitination PhosphoSitePlus
R1549 Methylation PhosphoSitePlus
K1560 Sumoylation PhosphoSitePlus
K1560 Ubiquitination PhosphoSitePlus
Y1594 Phosphorylation PhosphoSitePlus
K1597 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S222 Phosphorylation HPRD 20068231
S249 Phosphorylation HPRD 19691289, 20068231
S264 Phosphorylation HPRD 20068231
S265 Phosphorylation HPRD 18669648
S270 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S272 Phosphorylation HPRD 16964243, 20068231
S277 Phosphorylation HPRD 18691976, 16964243, 18452278, ...19651622, 18669648, 20068231
S289 Phosphorylation HPRD 19651622, 18669648, 20068231
S294 Phosphorylation HPRD 18669648, 20068231
T296 Phosphorylation HPRD 18669648, 20068231
S298 Phosphorylation HPRD 18669648, 20068231
T302 Phosphorylation HPRD 20068231
S406 Phosphorylation HPRD 20068231
S452 Phosphorylation HPRD 18691976, 20068231
S457 Phosphorylation HPRD 18691976, 20068231
T480 Phosphorylation HPRD 20068231
S495 Phosphorylation HPRD 20068231
S576 Phosphorylation HPRD 20068231
S623 Phosphorylation HPRD 20068231
S660 Phosphorylation HPRD 18691976, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S222 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S249 N249 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S272 L272 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T302 M302 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S457 L457 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T480 M480 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]