iPTMnet Report for O95758 (PTBP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95758 / PTBP3_HUMAN
Protein Name Polypyrimidine tract-binding protein 3
Gene Name Name: PTBP3
Synonyms:ROD1;
Organism Homo sapiens (Human)

PRO ID PR:O95758
DAG View
PRO Name polypyrimidine tract-binding protein 3 (human)
Definition A regulator of differentiation 1 that is encoded in the genome of human.
Short Label hPTBP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95758 (PTBP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
K14 Ubiquitination PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K84 Sumoylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
Y130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
K137 Sumoylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K216 Sumoylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K257 Acetylation PhosphoSitePlus
K257 Sumoylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K264 Acetylation PhosphoSitePlus
K264 Sumoylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K423 Acetylation PhosphoSitePlus   UniProt 19608861
K423 Ubiquitination PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
T448 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus   UniProt 23186163
S464 Phosphorylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K506 Acetylation PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
K510 Acetylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K549 Acetylation PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
T551 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S4 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S58 Phosphorylation HPRD 20068231
S454 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 M14 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S56 L56 Biomuta DOID:363 / uterine cancer [ icgc ]
S123 I123 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y265 H265 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K269 N269 Biomuta DOID:263 / kidney cancer [ cosmic ]
T551 A551 Biomuta DOID:9256 / colorectal cancer [ cosmic ]