iPTMnet Report for O95704 (APBB3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95704 / APBB3_HUMAN
Protein Name Amyloid-beta A4 precursor protein-binding family B member 3
Gene Name Name: APBB3
Synonyms:FE65L2;
Organism Homo sapiens (Human)

PRO ID PR:O95704
DAG View
PRO Name amyloid-beta A4 precursor protein-binding family B member 3 (human)
Definition An amyloid-beta A4 precursor protein-binding family B member 3 that is encoded in the genome of human.
Short Label hAPBB3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95704 (APBB3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K138 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K218 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S439 R439 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
S440 F440 Biomuta DOID:4159 / skin cancer [ cosmic ]
S443 F443 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T463 A463 Biomuta DOID:363 / uterine cancer [ icgc ]