iPTMnet Report for O95677 (EYA4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95677 / EYA4_HUMAN
Protein Name Eyes absent homolog 4
Gene Name Name: EYA4
Organism Homo sapiens (Human)

PRO ID PR:O95677
DAG View
PRO Name eyes absent homolog 4 (human)
Definition An eyes absent homolog 4 that is encoded in the genome of human.
Short Label hEYA4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95677 (EYA4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
M1 Acetylation UniProt 19413330
S4 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
C16 S-Nitrosylation dbSNO 26338901
S19 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
K99 Sumoylation PhosphoSitePlus
S105 O-Glycosylation GlyGen 23301498, 35138101, 30379171, ...30620550, 34019948, 35254053
T112 O-Glycosylation GlyGen 23301498, 35138101, 30379171, ...30620550, 34019948, 35254053
T119 O-Glycosylation GlyGen 23301498, 35138101, 30379171, ...30620550, 34019948, 35254053
T121 O-Glycosylation GlyGen 23301498, 35138101, 30379171, ...30620550, 34019948, 35254053
S127 O-Glycosylation GlyGen 23301498, 35138101, 30379171, ...30620550, 34019948, 35254053
S128 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
K203 Sumoylation PhosphoSitePlus
T343 O-Glycosylation GlyGen 30379171
S346 O-Glycosylation GlyGen 30379171
S361 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...16964243
K507 Acetylation PhosphoSitePlus
T522 Phosphorylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S361 Phosphorylation HPRD 19651622, 18691976, 18669648, ...16964243, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S338 Phosphorylation HPRD 19651622, 18691976, 18669648, ...16964243, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S361 Phosphorylation HPRD 19651622, 18691976, 18669648, ...16964243, 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047344 (hEYA4/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 L11 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S19 T19 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S24 F24 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S27 A27 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T47 N47 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T119 I119 Biomuta DOID:3571 / liver cancer [ cosmic ]
K203 N203 Biomuta DOID:1324 / lung cancer [ cosmic ]
K507 E507 Biomuta DOID:4159 / skin cancer [ cosmic ]