Protein Information

Cytoscape View

UniProt AC / UniProt ID O95571 / ETHE1_HUMAN
Protein Name Persulfide dioxygenase ETHE1, mitochondrial precursor
Gene Name Name: ETHE1
Organism Homo sapiens (Human)

PRO ID PR:O95571
DAG View
PRO Name persulfide dioxygenase ETHE1, mitochondrial (human)
Definition A persulfide dioxygenase ETHE1, mitochondrial that is encoded in the genome of human.
Short Label hETHE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O95571 (ETHE1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y38 Phosphorylation PhosphoSitePlus
K66 Acetylation PhosphoSitePlus   UniProt 19608861
K66 Ubiquitination PhosphoSitePlus
Y74 Phosphorylation PhosphoSitePlus
C170 S-Nitrosylation dbSNO 2212679, 22126794
K172 Acetylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y38 F38 Biomuta DOID:5041 / esophageal cancer [ icgc ]
Y74 C74 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S218 R218 Biomuta DOID:3571 / liver cancer [ icgc ]