iPTMnet Report for O95568 (METTL18)
Protein Information
| UniProt AC / UniProt ID | O95568 / MET18_HUMAN |
| Protein Name | Histidine protein methyltransferase 1 homolog |
| Gene Name | Name: METTL18 Synonyms:ASTP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95568 |
| PRO Name | histidine protein methyltransferase 1 homolog (human) |
| Definition | A histidine protein methyltransferase 1 homolog that is encoded in the genome of human. |
| Short Label | hMETTL18 |
| Category | organism-gene |
DAG ViewO95568 (METTL18) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S49 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163 | ||
| S77 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S83 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S84 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y297 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S84 | R84 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |
