iPTMnet Report for O95544 (NADK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95544 / NADK_HUMAN
Protein Name NAD kinase
Gene Name Name: NADK
Organism Homo sapiens (Human)

PRO ID PR:O95544
DAG View
PRO Name NAD kinase (human)
Definition An NAD kinase that is encoded in the genome of human.
Short Label hNADK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95544 (NADK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
R45 Methylation PhosphoSitePlus
S46 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S48 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S55 Phosphorylation PhosphoSitePlus   UniProt 23186163
T56 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus
S64 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
K102 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K158 Acetylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
C349 Methylation IEDB 31844290
S381 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation HPRD 17322306, 18669648
S48 Phosphorylation HPRD 17322306, 18767875, 18669648, ...20058876
S50 Phosphorylation HPRD 18669648, 20058876
S64 Phosphorylation HPRD 18669648, 20058876, 18212344
Site PTM Type PTM Enzyme Score Source PMID
T231 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R45 H45 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S48 C48 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S50 L50 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S103 F103 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T231 M231 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]