iPTMnet Report for O95521 (PRAMEF1)
Protein Information
| UniProt AC / UniProt ID | O95521 / PRAM1_HUMAN |
| Protein Name | PRAME family member 1 |
| Gene Name | Name: PRAMEF1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95521 |
| PRO Name | PRAME family member 1 (human) |
| Definition | A PRAME family member 1 that is encoded in the genome of human. |
| Short Label | hPRAMEF1 |
| Category | organism-gene |
O95521 (PRAMEF1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y194 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K273 | Sumoylation | score1 | PhosphoSitePlus | |||
| S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y321 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S328 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T72 | K72 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| Y194 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y194 | H194 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ icgc ] DOID:2531 / hematologic cancer [ icgc ] DOID:1781 / thyroid cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] | |
| S314 | Y314 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
DAG View