iPTMnet Report for O95497 (VNN1)
Protein Information
| UniProt AC / UniProt ID | O95497 / VNN1_HUMAN |
| Protein Name | Pantetheinase precursor |
| Gene Name | Name: VNN1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95497 |
| PRO Name | pantetheinase (human) |
| Definition | A pantetheinase that is encoded in the genome of human. |
| Short Label | hVNN1 |
| Category | organism-gene |
O95497 (VNN1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| N38 | N-Glycosylation | score2 | GlyGen UniProt | 15084671 | ||
| N130 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 29391424 | ||
| Y134 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T275 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N283 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 23090970, 29391424, ... | ||
| S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K293 | Acetylation | score1 | PhosphoSitePlus | |||
| N315 | N-Glycosylation | score2 | GlyGen UniProt | 16335952 | ||
| N353 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 19159218, 24190977, ... | ||
| N487 | N-Glycosylation | score1 | GlyGen | 29391424 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N38 | S38 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y134 | C134 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| T275 | A275 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| N283 | T283 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |
DAG View