Protein Information

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UniProt AC / UniProt ID O95487 / SC24B_HUMAN
Protein Name Protein transport protein Sec24B
Gene Name Name: SEC24B
Organism Homo sapiens (Human)

PRO ID PR:O95487
DAG View
PRO Name protein transport protein Sec24B (human)
Definition A protein transport protein Sec24B that is encoded in the genome of human.
Short Label hSEC24B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95487 (SEC24B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
Y71 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation phospho.ELM   PhosphoSitePlus 16094384
S139 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S142 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S147 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S149 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S197 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
Y207 Phosphorylation PhosphoSitePlus
T212 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S226 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S228 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T232 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S235 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S238 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S245 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S253 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S255 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S258 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T259 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T261 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S269 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T270 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S310 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S311 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S311 Phosphorylation PhosphoSitePlus
S315 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T316 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T327 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T329 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T329 Phosphorylation PhosphoSitePlus   UniProt 23186163
T332 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T332 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T341 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T341 Phosphorylation phospho.ELM 18669648
S342 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T344 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
S347 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
T537 Phosphorylation PhosphoSitePlus
K551 Acetylation PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
S660 O-Glycosylation GlyGen 23301498, 27655845, 30397120, ...30059200, 21740066, 29351928, 22661428, 32119511, 28657654, 29237092
Y670 Phosphorylation PhosphoSitePlus
T804 Phosphorylation PhosphoSitePlus
S817 Phosphorylation PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
K836 Ubiquitination PhosphoSitePlus
K849 Ubiquitination PhosphoSitePlus
Y883 Phosphorylation PhosphoSitePlus
Y890 Phosphorylation PhosphoSitePlus
K988 Acetylation PhosphoSitePlus
Y1100 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K1147 Ubiquitination PhosphoSitePlus
K1152 Ubiquitination PhosphoSitePlus
T1154 Phosphorylation PhosphoSitePlus
S1220 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 24275569, ...16094384
Site PTM Type PTM Enzyme Score Source PMID
Y117 Phosphorylation HPRD 16094384
T332 Phosphorylation HPRD 18669648
T341 Phosphorylation HPRD 18669648
S1092 Phosphorylation HPRD 20068231
T1093 Phosphorylation HPRD 20068231
Y1100 Phosphorylation HPRD 18083107
S1224 Phosphorylation HPRD 19651622, 16094384
Site PTM Type PTM Enzyme Score Source PMID
T332 Phosphorylation HPRD 18669648
T341 Phosphorylation HPRD 18669648
S1057 Phosphorylation HPRD 20068231
T1058 Phosphorylation HPRD 20068231
Y1065 Phosphorylation HPRD 18083107
S1189 Phosphorylation HPRD 19651622, 17081983
Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049185 (hSEC24B/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S68 P68 Biomuta DOID:3571 / liver cancer [ tcga ]
S226 * Biomuta DOID:9256 / colorectal cancer [ icgc ]
S235 N235 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S255 L255 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S269 L269 Biomuta DOID:4362 / cervical cancer [ tcga ]
S311 N311 Biomuta DOID:363 / uterine cancer [ tcga ]
K836 N836 Biomuta DOID:1612 / breast cancer [ icgc ]
K1147 T1147 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S1220 N1220 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]