iPTMnet Report for O95486 (SEC24A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95486 / SC24A_HUMAN
Protein Name Protein transport protein Sec24A
Gene Name Name: SEC24A
Organism Homo sapiens (Human)

PRO ID PR:O95486
DAG View
PRO Name protein transport protein Sec24A (human)
Definition A protein transport protein Sec24A that is encoded in the genome of human.
Short Label hSEC24A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95486 (SEC24A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
R88 Methylation PhosphoSitePlus
R107 Methylation PhosphoSitePlus
S156 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
S156 Phosphorylation PhosphoSitePlus
S157 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
T160 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
S162 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 32938750, 34019948, 29351928, 35132862, 36240223, 35254053
T165 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
T168 O-Glycosylation GlyGen 34846842
T169 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
S175 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
S176 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
S180 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
R222 Methylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
R232 Methylation PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
S314 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
T363 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
T391 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
T396 Phosphorylation PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K650 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
Y708 Phosphorylation PhosphoSitePlus
K733 Ubiquitination PhosphoSitePlus
K813 Acetylation PhosphoSitePlus
S961 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30397120, 32574038, 34019948, 29351928, 35132862, 36240223, 35254053
K1062 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T916 Phosphorylation HPRD 17322306


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049184 (hSEC24A/PhosRes+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T160 I160 Biomuta DOID:10283 / prostate cancer [ icgc ]
S175 Y175 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R222 M222 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T225 M225 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R232 K232 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S314 F314 Biomuta DOID:4159 / skin cancer [ cosmic ]
S392 C392 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K404 R404 Biomuta DOID:3571 / liver cancer [ cosmic ]
K404 N404 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K662 N662 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y708 H708 Biomuta DOID:10534 / stomach cancer [ cosmic ]