iPTMnet Report for O95479 (H6PD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95479 / G6PE_HUMAN
Protein Name GDH/6PGL endoplasmic bifunctional protein precursor
Gene Name Name: H6PD
Synonyms:GDH;
Organism Homo sapiens (Human)

PRO ID PR:O95479
DAG View
PRO Name GDH/6PGL endoplasmic bifunctional protein (human)
Definition A GDH/6PGL endoplasmic bifunctional protein that is encoded in the genome of human.
Short Label hH6PD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95479 (H6PD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y117 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
N157 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K223 Ubiquitination PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
N282 N-Glycosylation GlyGen   UniProt 34089345, 19159218, 24190977
R301 Methylation PhosphoSitePlus
R305 Methylation PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
Y449 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R301 Q301 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S730 I730 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]