iPTMnet Report for O95477 (ABCA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95477 / ABCA1_HUMAN
Protein Name Phospholipid-transporting ATPase ABCA1
Gene Name Name: ABCA1
Synonyms:ABC1,CERP;
Organism Homo sapiens (Human)

PRO ID PR:O95477
DAG View
PRO Name phospholipid-transporting ATPase ABCA1 (human)
Definition A phospholipid-transporting ATPase ABCA1 that is encoded in the genome of human.
Short Label hABCA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95477 (ABCA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N98 N-Glycosylation GlyGen   UniProt 19159218, 24190977
S116 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
N244 N-Glycosylation GlyGen   UniProt 19159218, 24190977
Y325 Phosphorylation PhosphoSitePlus
S350 O-Glycosylation GlyGen 29351928
N489 N-Glycosylation GlyGen 24190977
S884 Phosphorylation PhosphoSitePlus
S1031 Phosphorylation PhosphoSitePlus
S1042 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 12196520
S1042 Phosphorylation P17612 (PRKACA) HPRD   PhosphoSitePlus 12196520
S1145 Phosphorylation PhosphoSitePlus
Y1206 Phosphorylation PhosphoSitePlus
T1242 Phosphorylation phospho.ELM   PhosphoSitePlus 15218032
T1242 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15218032
T1243 Phosphorylation phospho.ELM   PhosphoSitePlus 15218032
T1243 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15218032
S1255 Phosphorylation phospho.ELM   PhosphoSitePlus 15218032
S1255 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15218032
S1262 Phosphorylation PhosphoSitePlus
T1286 Phosphorylation phospho.ELM   RLIMS-P 12869555
S1296 Phosphorylation PhosphoSitePlus
T1305 Phosphorylation phospho.ELM   RLIMS-P 12869555
S1536 Phosphorylation PhosphoSitePlus
S1540 Phosphorylation PhosphoSitePlus
S1548 Phosphorylation PhosphoSitePlus
T1582 Phosphorylation HPRD   PhosphoSitePlus 18452278
T1586 Phosphorylation HPRD   PhosphoSitePlus 18452278
N1637 N-Glycosylation GlyGen 29741879, 24190977
K2050 Acetylation PhosphoSitePlus
S2054 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12196520, 26494466
S2054 Phosphorylation P00533 (EGFR) PhosphoSitePlus   Signor 12196520, 26494466
S2054 Phosphorylation P17612 (PRKACA) HPRD   PhosphoSitePlus 12196520
S2101 Phosphorylation PhosphoSitePlus
S2234 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N98 S98 Biomuta DOID:363 / uterine cancer [ icgc ]
S884 L884 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1042 F1042 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1255 R1255 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1536 F1536 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
T1586 S1586 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1586 I1586 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N1637 D1637 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2101 F2101 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]