iPTMnet Report for O95467 (GNAS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95467 / GNAS3_HUMAN
Protein Name Neuroendocrine secretory protein 55 precursor
Gene Name Name: GNAS
Synonyms:GNAS1;
Organism Homo sapiens (Human)

Interactive Sequence View

Select/align proteoforms across species


O95467 (GNAS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
S153 O-Glycosylation PhosphoSitePlus
T154 O-Glycosylation PhosphoSitePlus
S158 O-Glycosylation PhosphoSitePlus
T160 O-Glycosylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
S170 O-Glycosylation PhosphoSitePlus
S174 O-Glycosylation PhosphoSitePlus
S176 O-Glycosylation PhosphoSitePlus
S181 O-Glycosylation PhosphoSitePlus
T182 O-Glycosylation PhosphoSitePlus
S187 O-Glycosylation PhosphoSitePlus
R227 Methylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S158 F158 Biomuta DOID:1319 / brain cancer [ icgc ]
S170 N170 Biomuta DOID:4159 / skin cancer [ cosmic ]
S174 C174 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T182 A182 Biomuta DOID:4159 / skin cancer [ cosmic ]
R227 H227 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
S230 T230 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]