iPTMnet Report for O95427 (PIGN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95427 / PIGN_HUMAN
Protein Name GPI ethanolamine phosphate transferase 1
Gene Name Name: PIGN
Synonyms:MCD4;
Organism Homo sapiens (Human)

PRO ID PR:O95427
DAG View
PRO Name GPI ethanolamine phosphate transferase 1 (human)
Definition A GPI ethanolamine phosphate transferase 1 that is encoded in the genome of human.
Short Label hPIGN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95427 (PIGN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K117 Ubiquitination PhosphoSitePlus
N128 N-Glycosylation GlyGen 29741879, 24190977
K162 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
N191 N-Glycosylation GlyGen 24190977
N192 N-Glycosylation GlyGen 24190977
S223 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K404 Methylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K927 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K162 E162 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
N192 S192 Biomuta DOID:3571 / liver cancer [ cosmic ]
K471 Q471 Biomuta DOID:9256 / colorectal cancer [ cosmic ]