iPTMnet Report for O95409 (ZIC2)
Protein Information
| UniProt AC / UniProt ID | O95409 / ZIC2_HUMAN |
| Protein Name | Zinc finger protein ZIC 2 |
| Gene Name | Name: ZIC2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95409 |
| PRO Name | zinc finger protein ZIC 2 (human) |
| Definition | A zinc finger protein ZIC 2 that is encoded in the genome of human. |
| Short Label | hZIC2 |
| Category | organism-gene |
DAG ViewO95409 (ZIC2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| E192 | Phosphorylation | score2 | IntAct | 18097573 | ||
| S199 | Phosphorylation | score4 | HPRD neXtProt PhosphoSitePlus | 18068128, 20068231 | ||
| K253 | Sumoylation | score1 | PhosphoSitePlus | |||
| K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T276 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T328 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K342 | Acetylation | score1 | PhosphoSitePlus | |||
| T356 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T358 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T328 | I328 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K342 | Q342 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K342 | N342 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
