Protein Information

Cytoscape View


UniProt AC / UniProt ID O95405 / ZFYV9_HUMAN
Protein Name Zinc finger FYVE domain-containing protein 9
Gene Name Name: ZFYVE9
Synonyms:MADHIP,SARA,SMADIP;
Organism Homo sapiens (Human)

PRO ID PR:O95405
DAG View
PRO Name sara (human)
Definition A sara that is encoded in the genome of human.
Short Label hZFYVE9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95405 (ZFYVE9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T26 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus   UniProt 23186163
S309 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
T503 Phosphorylation PhosphoSitePlus
Y516 Phosphorylation PhosphoSitePlus
Y520 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y1082 Phosphorylation PhosphoSitePlus
S1091 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T302 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T302 Phosphorylation HPRD   phospho.ELM 18669648


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:O95405-1 (hZFYVE9/iso:1) Interaction PR:P08100 (hRHO) PRO 17693260
PR:O95405-1 (hZFYVE9/iso:1) Interaction PR:000025960 (hSMAD2/iso:[Long/Short]/UnPhos:1) PRO 11877415, 9865696
PR:P84022-1 (hSMAD3/iso:1) Interaction PR:O95405-1 (hZFYVE9/iso:1) PRO 12154125


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S257 F257 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
T275 I275 Biomuta DOID:3070 / malignant glioma [ tcga ]
S314 N314 Biomuta DOID:1612 / breast cancer [ cosmic ]
S668 I668 Biomuta DOID:10534 / stomach cancer [ tcga ]