iPTMnet Report for O95405 (ZFYVE9)
Protein Information
| UniProt AC / UniProt ID | O95405 / ZFYV9_HUMAN |
| Protein Name | Zinc finger FYVE domain-containing protein 9 |
| Gene Name | Name: ZFYVE9 Synonyms:MADHIP,SARA,SMADIP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95405 |
| PRO Name | zinc finger FYVE domain-containing protein 9 (human) |
| Definition | A zinc finger FYVE domain-containing protein 9 that is encoded in the genome of human. |
| Short Label | hZFYVE9 |
| Category | organism-gene |
DAG ViewO95405 (ZFYVE9) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S257 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T275 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T302 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S306 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S309 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S501 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T503 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y516 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S562 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S568 | O-Glycosylation | score1 | GlyGen | 23301498, 28657654 | ||
| S635 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S668 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| Y1082 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1091 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T302 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 |
Proteoform PPIs
|
Protein 1 | Relation | Protein 2 | Source | PMID |
|---|---|---|---|---|---|
| PR:O95405-1 (hZFYVE9/iso:1) | Interaction | PR:P08100 (hRHO) | PRO | 17693260 | |
| PR:O95405-1 (hZFYVE9/iso:1) | Interaction | PR:000025960 (hSMAD2/iso:[Long/Short]/UnPhos:1) | PRO | 11877415, 9865696 | |
| PR:P84022-1 (hSMAD3/iso:1) | Interaction | PR:O95405-1 (hZFYVE9/iso:1) | PRO | 12154125 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S257 | F257 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T275 | I275 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S314 | N314 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S568 | N568 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S635 | T635 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S668 | I668 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S1091 | N1091 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
