iPTMnet Report for O95400 (CD2BP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95400 / CD2B2_HUMAN
Protein Name CD2 antigen cytoplasmic tail-binding protein 2
Gene Name Name: CD2BP2
Synonyms:KIAA1178;
Organism Homo sapiens (Human)

PRO ID PR:O95400
DAG View
PRO Name CD2 antigen cytoplasmic tail-binding protein 2 (human)
Definition A CD2 cytoplasmic tail-binding protein 2 that is encoded in the genome of human.
Short Label hCD2BP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95400 (CD2BP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K26 Sumoylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S39 O-Glycosylation GlyGen 34019948, 29351928
S46 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19007248, 24275569
S49 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 17081983, ...18452278, 19651622, 19367720, 18669648, 24275569, 17693683, 23186163, 18318008, 20068231
S60 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
S118 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K127 Ubiquitination PhosphoSitePlus
S139 Phosphorylation HPRD   PhosphoSitePlus 20068231, 18452278
S141 Phosphorylation HPRD   PhosphoSitePlus 20068231, 18452278
T150 Phosphorylation HPRD 17081983
S151 Phosphorylation HPRD 17081983
R176 Methylation PhosphoSitePlus
R181 Methylation PhosphoSitePlus
S194 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 18767875, 19664995, ...19651622, 17322306, 20068231
S195 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 23186163, 17081983, ...18767875, 19664995, 19651622, 18669648, 20068231, 17924679
T243 Phosphorylation HPRD   PhosphoSitePlus 18452278
S247 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
K321 Sumoylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
K333 Acetylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S39 I39 Biomuta DOID:263 / kidney cancer [ cosmic ]
S46 T46 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S46 F46 Biomuta [ cosmic ]
S49 I49 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S60 Y60 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S61 N61 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R181 Q181 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S247 P247 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S332 T332 Biomuta DOID:9256 / colorectal cancer [ cosmic ]