Protein Information

Cytoscape View


UniProt AC / UniProt ID O95398 / RPGF3_HUMAN
Protein Name Rap guanine nucleotide exchange factor 3
Gene Name Name: RAPGEF3
Synonyms:CGEF1,EPAC,EPAC1;
Organism Homo sapiens (Human)

PRO ID PR:O95398
DAG View
PRO Name Rap guanine nucleotide exchange factor 3 (human)
Definition A Rap guanine nucleotide exchange factor 3 that is encoded in the genome of human.
Short Label hRAPGEF3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95398 (RAPGEF3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S82 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
K268 Acetylation PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S864 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S108 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S82 F82 Biomuta DOID:4159 / skin cancer [ cosmic ]
S494 P494 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]