iPTMnet Report for O95396 (MOCS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95396 / MOCS3_HUMAN
Protein Name Adenylyltransferase and sulfurtransferase MOCS3
Gene Name Name: MOCS3
Synonyms:UBA4;
Organism Homo sapiens (Human)

PRO ID PR:O95396
DAG View
PRO Name adenylyltransferase and sulfurtransferase MOCS3 (human)
Definition An adenylyltransferase and sulfurtransferase MOCS3 that is encoded in the genome of human.
Short Label hMOCS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95396 (MOCS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K25 Ubiquitination PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
C179 Methylation IEDB 31844290
Y187 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S47 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S47 L47 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
S144 L144 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S150 L150 Biomuta DOID:1612 / breast cancer [ cosmic ]
K390 Q390 Biomuta DOID:4606 / bile duct cancer [ cosmic ]