iPTMnet Report for O95391 (SLU7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95391 / SLU7_HUMAN
Protein Name Pre-mRNA-splicing factor SLU7
Gene Name Name: SLU7
Organism Homo sapiens (Human)

PRO ID PR:O95391
DAG View
PRO Name pre-mRNA-splicing factor SLU7 (human)
Definition A pre-mRNA-splicing factor SLU7 that is encoded in the genome of human.
Short Label hSLU7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95391 (SLU7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S15 Phosphorylation HPRD   PhosphoSitePlus 20068231
K44 Sumoylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
Y102 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
S110 O-Glycosylation GlyGen 30379171
S110 Phosphorylation HPRD   PhosphoSitePlus 19413330
K131 Ubiquitination PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K187 Sumoylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K199 Sumoylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
S215 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 19413330, 19007248, 19664995, 19651622, 24275569, 20166139, 17924679, 20068231, 17081983
S227 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S235 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 18452278, ...19651622, 24275569, 20068231
Y243 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
K257 Sumoylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
T261 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
K302 Acetylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
Y354 Phosphorylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
Y400 Phosphorylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
K418 Sumoylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
K482 Sumoylation PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
K540 Acetylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 L15 Biomuta DOID:1324 / lung cancer [ cosmic ]
K44 N44 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S110 F110 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S110 P110 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S227 Y227 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K257 N257 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K288 N288 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K408 Q408 Biomuta DOID:263 / kidney cancer [ cosmic ]