Protein Information

Cytoscape View


UniProt AC / UniProt ID O95372 / LYPA2_HUMAN
Protein Name Acyl-protein thioesterase 2
Gene Name Name: LYPLA2
Synonyms:APT2;
Organism Homo sapiens (Human)

PRO ID PR:O95372
DAG View
PRO Name acyl-protein thioesterase 2 (human)
Definition An acyl-protein thioesterase 2 that is encoded in the genome of human.
Short Label hLYPLA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95372 (LYPLA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
C56 S-Nitrosylation dbSNO 19483679
K100 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K190 Acetylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K226 E226 Biomuta DOID:2531 / hematologic cancer [ cosmic ]