iPTMnet Report for O95363 (FARS2)
Protein Information
| UniProt AC / UniProt ID | O95363 / SYFM_HUMAN |
| Protein Name | Phenylalanine--tRNA ligase, mitochondrial precursor |
| Gene Name | Name: FARS2 Synonyms:FARS1;ORFNames:HSPC320; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95363 |
| PRO Name | phenylalanine--tRNA ligase, mitochondrial (human) |
| Definition | A phenylalanine--tRNA ligase, mitochondrial that is encoded in the genome of human. |
| Short Label | hFARS2 |
| Category | organism-gene |
DAG ViewO95363 (FARS2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K202 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T387 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K56 | T56 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K351 | M351 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T387 | I387 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
