Protein Information

Cytoscape View


UniProt AC / UniProt ID O95342 / ABCBB_HUMAN
Protein Name Bile salt export pump
Gene Name Name: ABCB11
Synonyms:BSEP;
Organism Homo sapiens (Human)

PRO ID PR:O95342
DAG View
PRO Name bile salt export pump (human)
Definition A bile salt export pump that is encoded in the genome of human.
Short Label hABCB11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95342 (ABCB11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
N109 N-Glycosylation UniProt 17082223
N116 N-Glycosylation UniProt 17082223
N122 N-Glycosylation UniProt 17082223
N125 N-Glycosylation UniProt 17082223
T586 Phosphorylation PhosphoSitePlus   UniProt 24275569
S587 Phosphorylation PhosphoSitePlus   UniProt 24275569
S593 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
S686 Phosphorylation HPRD   PhosphoSitePlus 20166139
S690 Phosphorylation PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus   UniProt 24275569
T858 Phosphorylation PhosphoSitePlus
T859 Phosphorylation PhosphoSitePlus
S1214 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1217 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N122 D122 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S683 R683 Biomuta DOID:3571 / liver cancer [ icgc ]
S690 C690 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]