Protein Information

Cytoscape View

UniProt AC / UniProt ID O95256 / I18RA_HUMAN
Protein Name Interleukin-18 receptor accessory protein precursor
Gene Name Name: IL18RAP
Organism Homo sapiens (Human)

PRO ID PR:O95256
DAG View
PRO Name interleukin-18 receptor accessory protein (human)
Definition An interleukin-18 receptor accessory protein that is encoded in the genome of human.
Short Label hIL18RAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O95256 (IL18RAP) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N119 N-Glycosylation GlyGen   UniProt 25500532
S133 Phosphorylation PhosphoSitePlus
N152 N-Glycosylation GlyGen   UniProt 25500532
S294 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
N345 N-Glycosylation GlyGen   UniProt 25500532
T401 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
K543 Acetylation PhosphoSitePlus
K554 Acetylation PhosphoSitePlus
K554 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S133 R133 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S294 C294 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S294 Y294 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S307 G307 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S342 P342 Biomuta DOID:5041 / esophageal cancer [ icgc ]
T401 M401 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1612 / breast cancer [ icgc ]
T401 A401 Biomuta DOID:3070 / malignant glioma [ tcga ]
S469 I469 Biomuta DOID:3571 / liver cancer [ icgc ]