iPTMnet Report for O95235 (KIF20A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95235 / KI20A_HUMAN
Protein Name Kinesin-like protein KIF20A
Gene Name Name: KIF20A
Synonyms:MKLP2,RAB6KIFL;
Organism Homo sapiens (Human)

PRO ID PR:O95235
DAG View
PRO Name kinesin-like protein KIF20A (human)
Definition A kinesin-like protein KIF20A that is encoded in the genome of human.
Short Label hKIF20A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95235 (KIF20A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 20068231
S2 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus   UniProt 20068231
S14 Phosphorylation PhosphoSitePlus   UniProt 20068231
S21 Phosphorylation PhosphoSitePlus   UniProt 20068231
S33 Phosphorylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S58 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
S244 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
Y246 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
S256 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S259 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
S528 Phosphorylation IEDB   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   UniProt 12939256, 18669648, 27920218, ...16565220
S532 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...16565220, 18669648, 20068231
K537 Ubiquitination PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
T543 Phosphorylation PhosphoSitePlus
S556 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
Y558 Phosphorylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
Y637 Phosphorylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
S662 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 12939256, 18220336
S668 Phosphorylation PhosphoSitePlus   UniProt 12939256
S670 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S677 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
S685 Phosphorylation PhosphoSitePlus   UniProt 23186163
T686 Phosphorylation PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
K712 Ubiquitination PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
S754 Phosphorylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus
K770 Acetylation PhosphoSitePlus
C778 Methylation IEDB 31844290
C809 Methylation IEDB 31844290
K819 Ubiquitination PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus   UniProt 20068231
K827 Ubiquitination PhosphoSitePlus
T832 Phosphorylation PhosphoSitePlus
T857 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
T859 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S862 Phosphorylation PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
T864 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S867 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16565220
Y869 Phosphorylation PhosphoSitePlus
S875 Phosphorylation PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus   RLIMS-P+   Signor   UniProt 23186163, 27939310
S878 Phosphorylation Q96GD4 (AURKB) RLIMS-P+   Signor 27939310
S883 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 20068231
S14 Phosphorylation HPRD 20068231
S21 Phosphorylation HPRD 19007248, 20068231
S26 Phosphorylation HPRD 20068231
T27 Phosphorylation HPRD 20068231
S33 Phosphorylation HPRD 20068231
S49 Phosphorylation HPRD 19691289, 20068231, 16565220
S58 Phosphorylation HPRD 19691289
S238 Phosphorylation HPRD 19007248
S244 Phosphorylation HPRD 16565220, 19691289, 19007248
Y246 Phosphorylation HPRD 19007248, 19691289
S249 Phosphorylation HPRD 19007248, 19691289
S256 Phosphorylation HPRD 18669648
S405 Phosphorylation HPRD 20068230
Y491 Phosphorylation HPRD 20068231
S528 Phosphorylation HPRD 18669648, 16565220, 19691289, ...20068231, 19007248
S532 Phosphorylation HPRD 18691976, 19691289, 16565220, ...18669648, 19007248, 19415658, 20068231
S534 Phosphorylation HPRD 19691289, 20068231
S556 Phosphorylation HPRD 16565220, 19691289, 19007248
T572 Phosphorylation HPRD 19664994
S635 Phosphorylation HPRD 20068231
S662 Phosphorylation HPRD 18691976, 19691289, 20068231
S668 Phosphorylation HPRD 19691289
S670 Phosphorylation HPRD 19007248, 20068231, 19691289
S683 Phosphorylation HPRD 19007248, 19691289
S685 Phosphorylation HPRD 19691289
S825 Phosphorylation HPRD 19007248, 20068231, 19691289
T857 Phosphorylation HPRD 18669648
T859 Phosphorylation HPRD 18669648
T864 Phosphorylation HPRD 18669648
S867 Phosphorylation HPRD 19413330, 18669648, 16565220, ...19691289, 19007248
Y869 Phosphorylation HPRD 19691289


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048110 (hKIF20A/InitMet-/Phos:1) pS528 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 Y7 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S21 F21 Biomuta DOID:4159 / skin cancer [ cosmic ]
S44 F44 Biomuta DOID:1324 / lung cancer [ cosmic ]
S47 F47 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S109 I109 Biomuta DOID:3571 / liver cancer [ cosmic ]
S226 P226 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K242 N242 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S522 L522 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S522 T522 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S532 F532 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S635 R635 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S635 I635 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y637 * Biomuta DOID:3571 / liver cancer [ cosmic ]
T832 A832 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T859 I859 Biomuta [ cosmic ]
S863 T863 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S867 I867 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S883 F883 Biomuta DOID:363 / uterine cancer [ icgc ]