iPTMnet Report for O95232 (LUC7L3)
Protein Information
UniProt AC / UniProt ID | O95232 / LC7L3_HUMAN |
Protein Name | Luc7-like protein 3 |
Gene Name | Name: LUC7L3 Synonyms:CREAP1,CROP,O48; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95232 |
PRO Name | Luc7-like protein 3 (human) |
Definition | A cisplatin resistance-associated overexpressed protein that is encoded in the genome of human. |
Short Label | hLUC7L3 |
Category | organism-gene |
O95232 (LUC7L3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895, ... | ||
S3 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
C35 | Methylation | score1 | IEDB | 31844290 | ||
K36 | Acetylation | score1 | PhosphoSitePlus | |||
Y38 | Phosphorylation | score1 | PhosphoSitePlus | |||
R67 | Methylation | score1 | PhosphoSitePlus | |||
K78 | Acetylation | score1 | PhosphoSitePlus | |||
S110 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163 | ||
S115 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
K166 | Acetylation | score1 | PhosphoSitePlus | |||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
K231 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
T238 | Phosphorylation | score1 | PhosphoSitePlus | |||
S295 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
S297 | O-Glycosylation | score1 | GlyGen | 33214551, 34725712, 34019948, ... | ||
S325 | Phosphorylation | score1 | PhosphoSitePlus | |||
S327 | Phosphorylation | score1 | PhosphoSitePlus | |||
S333 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S335 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
S345 | Phosphorylation | score1 | PhosphoSitePlus | |||
S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
S389 | Phosphorylation | score1 | PhosphoSitePlus | |||
S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
S393 | Phosphorylation | score1 | PhosphoSitePlus | |||
T405 | Phosphorylation | score1 | PhosphoSitePlus | |||
S410 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
T412 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
T419 | O-Glycosylation | score1 | GlyGen | 33214551, 34725712, 34019948, ... | ||
T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
S420 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692 | ||
K424 | Sumoylation | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163, 21406692, ... | ||
T429 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332, 18669648 | ||
S431 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score0 | HPRD | 20068231 | ||
S110 | Phosphorylation | score0 | HPRD | 17525332, 18077418 | ||
S115 | Phosphorylation | score0 | HPRD | 19413330, 20068231 | ||
T238 | Phosphorylation | score0 | HPRD | 20068231 | ||
S333 | Phosphorylation | score0 | HPRD | 20068231 | ||
S335 | Phosphorylation | score0 | HPRD | 20068231 | ||
S339 | Phosphorylation | score0 | HPRD | 20068231 | ||
S420 | Phosphorylation | score0 | HPRD | 18669648 | ||
S425 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 18077418, ... | ||
T429 | Phosphorylation | score0 | HPRD | 18077418, 17525332, 18669648, ... | ||
S431 | Phosphorylation | score0 | HPRD | 19413330, 18077418, 19664995, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y38 | H38 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
R67 | * | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
R67 | Q67 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
K78 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S115 | C115 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K135 | E135 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S295 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
S345 | Y345 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S390 | I390 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S393 | P393 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
S393 | F393 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
T405 | P405 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
T405 | A405 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S431 | F431 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |