iPTMnet Report for O95219 (SNX4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95219 / SNX4_HUMAN
Protein Name Sorting nexin-4
Gene Name Name: SNX4
Organism Homo sapiens (Human)

PRO ID PR:O95219
DAG View
PRO Name sorting nexin-4 (human)
Definition A sorting nexin-4 that is encoded in the genome of human.
Short Label hSNX4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95219 (SNX4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S22 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K33 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
C172 Methylation IEDB 31844290
C172 S-Nitrosylation dbSNO 19483679
K199 Ubiquitination PhosphoSitePlus
K205 Methylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
R247 Methylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
K356 Methylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K419 Acetylation PhosphoSitePlus
Y425 Phosphorylation PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 C22 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S89 T89 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S97 R97 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T347 I347 Biomuta DOID:363 / uterine cancer [ icgc ]
S354 F354 Biomuta DOID:4159 / skin cancer [ cosmic ]
K356 R356 Biomuta DOID:4159 / skin cancer [ cosmic ]
K356 M356 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]