iPTMnet Report for O95202 (LETM1)
Protein Information
UniProt AC / UniProt ID | O95202 / LETM1_HUMAN |
Protein Name | Mitochondrial proton/calcium exchanger protein precursor |
Gene Name | Name: LETM1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95202 |
PRO Name | mitochondrial proton/calcium exchanger protein (human) |
Definition | A mitochondrial proton/calcium exchanger protein that is encoded in the genome of human. |
Short Label | hLETM1 |
Category | organism-gene |
O95202 (LETM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y141 | Phosphorylation | score1 | PhosphoSitePlus | |||
S142 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y164 | Phosphorylation | score1 | PhosphoSitePlus | |||
T175 | Phosphorylation | score1 | PhosphoSitePlus | |||
S190 | Phosphorylation | score1 | PhosphoSitePlus | |||
T192 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 29123128 | ||
K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
K284 | Acetylation | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
R307 | Methylation | score1 | PhosphoSitePlus | |||
K373 | Ubiquitination | score1 | PhosphoSitePlus | |||
R393 | Methylation | score1 | PhosphoSitePlus | |||
C552 | Methylation | score1 | IEDB | 31844290 | ||
Y579 | Phosphorylation | score1 | PhosphoSitePlus | |||
S580 | Phosphorylation | score1 | PhosphoSitePlus | |||
K597 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S602 | Phosphorylation | score1 | PhosphoSitePlus | |||
T643 | Phosphorylation | score1 | PhosphoSitePlus | |||
S649 | Phosphorylation | score1 | PhosphoSitePlus | |||
S666 | Phosphorylation | score1 | PhosphoSitePlus | |||
K682 | Ubiquitination | score1 | PhosphoSitePlus | |||
S739 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T239 | K239 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K252 | N252 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S287 | Y287 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
R307 | C307 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R307 | L307 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K373 | N373 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S580 | R580 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] |