iPTMnet Report for O95185 (UNC5C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95185 / UNC5C_HUMAN
Protein Name Netrin receptor UNC5C precursor
Gene Name Name: UNC5C
Synonyms:UNC5H3;
Organism Homo sapiens (Human)

PRO ID PR:O95185
DAG View
PRO Name netrin receptor UNC5C (human)
Definition A netrin receptor UNC5C that is encoded in the genome of human.
Short Label hUNC5C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95185 (UNC5C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S123 Phosphorylation PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
Y449 Phosphorylation PRO
Y454 Phosphorylation PRO   PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
T506 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
Y568 Phosphorylation PRO
T570 O-Glycosylation GlyGen 31492838
Y649 Phosphorylation PRO
Y667 Phosphorylation PRO
T674 Phosphorylation PhosphoSitePlus
C779 Methylation IEDB 31844290
T832 Phosphorylation PhosphoSitePlus
S843 Phosphorylation PhosphoSitePlus
S854 Phosphorylation PhosphoSitePlus
T861 Phosphorylation PhosphoSitePlus
Y878 Phosphorylation PhosphoSitePlus
Y881 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049621 (hUNC5C/SigPep-/Phos:1) pY449,pY454,pY568,pY649,pY667 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S127 L127 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T311 K311 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T311 A311 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y449 H449 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T484 N484 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T506 I506 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S516 N516 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y568 F568 Biomuta DOID:3571 / liver cancer [ cosmic ]
T570 I570 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y667 N667 Biomuta DOID:1324 / lung cancer [ cosmic ]
T861 M861 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y881 * Biomuta [ cosmic ]