iPTMnet Report for O95163 (ELP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95163 / ELP1_HUMAN
Protein Name Elongator complex protein 1
Gene Name Name: ELP1
Synonyms:IKAP;
Organism Homo sapiens (Human)

PRO ID PR:O95163
DAG View
PRO Name elongator complex protein 1 (human)
Definition An elongator complex protein 1 that is encoded in the genome of human.
Short Label hELP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95163 (ELP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K157 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
S471 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K474 Methylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
T699 Phosphorylation PhosphoSitePlus
T705 Phosphorylation PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
K735 Ubiquitination PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
Y797 Phosphorylation HPRD 20068231
S803 Phosphorylation PhosphoSitePlus
S804 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y806 Phosphorylation PhosphoSitePlus
K815 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
K846 Ubiquitination PhosphoSitePlus
K857 Ubiquitination PhosphoSitePlus
S867 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K915 Ubiquitination PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
K926 Ubiquitination PhosphoSitePlus
T935 Phosphorylation PhosphoSitePlus
K938 Ubiquitination PhosphoSitePlus
K945 Ubiquitination PhosphoSitePlus
K952 Ubiquitination PhosphoSitePlus
K966 Ubiquitination PhosphoSitePlus
K968 Ubiquitination PhosphoSitePlus
K1055 Ubiquitination PhosphoSitePlus
K1098 Ubiquitination PhosphoSitePlus
K1110 Ubiquitination PhosphoSitePlus
S1171 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1174 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1190 Phosphorylation PhosphoSitePlus
K1208 Ubiquitination PhosphoSitePlus
S1211 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K484 M484 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S695 A695 Biomuta DOID:4159 / skin cancer [ cosmic ]
K794 N794 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S804 G804 Biomuta DOID:1324 / lung cancer [ cosmic ]
S804 I804 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K834 R834 Biomuta DOID:1324 / lung cancer [ cosmic ]
K925 R925 Biomuta DOID:4159 / skin cancer [ cosmic ]
K938 E938 Biomuta DOID:3571 / liver cancer [ cosmic ]
K945 R945 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K952 I952 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1110 N1110 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1190 L1190 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]