Protein Information

Cytoscape View


UniProt AC / UniProt ID O95104 / SCAF4_HUMAN
Protein Name SR-related and CTD-associated factor 4
Gene Name Name: SCAF4
Synonyms:KIAA1172;
Organism Homo sapiens (Human)

PRO ID PR:O95104
DAG View
PRO Name SR-related and CTD-associated factor 4 (human)
Definition An SR-related and CTD-associated factor 4 that is encoded in the genome of human.
Short Label hSCAF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95104 (SCAF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K49 Acetylation PhosphoSitePlus   UniProt 19608861
S73 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
T149 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S154 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 18669648, ...24275569, 19690332
T236 Phosphorylation PhosphoSitePlus
T237 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
Y267 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S473 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S476 Phosphorylation PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K583 Ubiquitination PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus
S656 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18220336
T819 O-Glycosylation GlyGen 23301498, 32119511, 29351928
R888 Methylation PhosphoSitePlus
R917 Methylation PhosphoSitePlus
R937 Methylation PhosphoSitePlus
R940 Methylation PhosphoSitePlus
S1004 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1037 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1054 Phosphorylation PhosphoSitePlus
S1068 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
R1086 Methylation PhosphoSitePlus
S1098 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T149 Phosphorylation HPRD 18669648, 20058876
S154 Phosphorylation HPRD 19413330, 18491316, 20058876, ...19664995, 18452278, 19651622, 18669648, 20068231
T237 Phosphorylation HPRD 15302935, 20068231
S656 Phosphorylation HPRD 19651622, 18452278
S1004 Phosphorylation HPRD 20068231
S1037 Phosphorylation HPRD 17081983, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K583 N583 Biomuta DOID:363 / uterine cancer [ tcga ]
R937 K937 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1004 Y1004 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:11054 / urinary bladder cancer [ tcga ]
S1098 N1098 Biomuta DOID:1793 / pancreatic cancer [ tcga ]