iPTMnet Report for O95081 (AGFG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95081 / AGFG2_HUMAN
Protein Name Arf-GAP domain and FG repeat-containing protein 2
Gene Name Name: AGFG2
Synonyms:HRBL,RABR;
Organism Homo sapiens (Human)

PRO ID PR:O95081
DAG View
PRO Name Arf-GAP domain and FG repeat-containing protein 2 (human)
Definition An Arf-GAP domain and FG repeat-containing protein 2 that is encoded in the genome of human.
Short Label hAGFG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95081 (AGFG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Acetylation PhosphoSitePlus
K7 Acetylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K141 Acetylation PhosphoSitePlus
K142 Acetylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
K173 Acetylation PhosphoSitePlus   UniProt 19608861
K173 Sumoylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
T177 O-Glycosylation GlyGen 34846842, 33214551, 28510447, ...35138101, 32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S185 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S187 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S191 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
T192 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S193 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S194 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S198 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S200 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S209 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S309 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S332 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S333 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...32574038, 34019948, 35254053, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654
S451 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S209 Phosphorylation HPRD 18510355
T210 Phosphorylation HPRD 18510355
S217 Phosphorylation HPRD 18510355
S451 Phosphorylation HPRD 18077418


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K138 N138 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K152 M152 Biomuta DOID:3571 / liver cancer [ cosmic ]
K152 N152 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K158 T158 Biomuta DOID:3571 / liver cancer [ cosmic ]
S187 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T192 N192 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S193 P193 Biomuta [ cosmic ]
S193 W193 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S194 R194 Biomuta DOID:3571 / liver cancer [ cosmic ]
S209 R209 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]