iPTMnet Report for O95025 (SEMA3D)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95025 / SEM3D_HUMAN
Protein Name Semaphorin-3D precursor
Gene Name Name: SEMA3D
ORFNames:UNQ760/PRO1491;
Organism Homo sapiens (Human)

PRO ID PR:O95025
DAG View
PRO Name semaphorin-3D (human)
Definition A semaphorin-3D that is encoded in the genome of human.
Short Label hSEMA3D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95025 (SEMA3D) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S218 Phosphorylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
Y447 Phosphorylation HPRD   PhosphoSitePlus 19664994
S660 Phosphorylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
K749 Acetylation PhosphoSitePlus
K758 Methylation PhosphoSitePlus
K759 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T222 A222 Biomuta DOID:363 / uterine cancer [ icgc ]
T439 A439 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S660 F660 Biomuta DOID:4159 / skin cancer [ cosmic ]
S709 T709 Biomuta DOID:1324 / lung cancer [ cosmic ]
K758 T758 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K758 N758 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]