Protein Information

Cytoscape View

UniProt AC / UniProt ID O95025 / SEM3D_HUMAN
Protein Name Semaphorin-3D precursor
Gene Name Name: SEMA3D
Organism Homo sapiens (Human)

PRO ID PR:O95025
DAG View
PRO Name semaphorin-3D (human)
Definition A semaphorin-3D that is encoded in the genome of human.
Short Label hSEMA3D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O95025 (SEMA3D) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S218 Phosphorylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
Y447 Phosphorylation HPRD   PhosphoSitePlus 19664994
S660 Phosphorylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
K749 Acetylation PhosphoSitePlus
K758 Methylation PhosphoSitePlus
K759 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T222 A222 Biomuta DOID:363 / uterine cancer [ tcga ]
T439 K439 Biomuta DOID:3571 / liver cancer [ icgc ]
K758 T758 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K758 N758 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1612 / breast cancer [ cosmic, icgc, tcga ] DOID:1909 / melanoma [ cosmic ]