Protein Information

Cytoscape View


UniProt AC / UniProt ID O94979 / SC31A_HUMAN
Protein Name Protein transport protein Sec31A
Gene Name Name: SEC31A
Synonyms:KIAA0905,SEC31L1;ORFNames:HSPC275,HSPC334;
Organism Homo sapiens (Human)

PRO ID PR:O94979
DAG View
PRO Name protein transport protein Sec31A (human)
Definition A protein transport protein Sec31A that is encoded in the genome of human.
Short Label hSEC31A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94979 (SEC31A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C60 S-Nitrosylation dbSNO 19483679
Y101 Phosphorylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
Y331 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S397 Phosphorylation PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
T467 Phosphorylation PhosphoSitePlus
K471 Methylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
R486 Methylation PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
Y495 Phosphorylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S527 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...24275569
S532 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983
S556 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus   UniProt 22358839
K661 Ubiquitination PhosphoSitePlus
K707 Ubiquitination PhosphoSitePlus
K729 Ubiquitination PhosphoSitePlus
S799 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 20068231
K801 Ubiquitination PhosphoSitePlus
Y804 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K806 Ubiquitination PhosphoSitePlus
Y831 Phosphorylation PhosphoSitePlus
R894 Methylation PhosphoSitePlus
T989 Phosphorylation PhosphoSitePlus
S1101 Phosphorylation PhosphoSitePlus
T1104 Phosphorylation PhosphoSitePlus
K1105 Acetylation PhosphoSitePlus
K1105 Ubiquitination PhosphoSitePlus
T1108 Phosphorylation PhosphoSitePlus
K1110 Ubiquitination PhosphoSitePlus
K1120 Ubiquitination PhosphoSitePlus
T1121 Phosphorylation PhosphoSitePlus
T1122 Phosphorylation PhosphoSitePlus
C1130 S-Nitrosylation dbSNO 24105792
K1140 Ubiquitination PhosphoSitePlus
Y1154 Phosphorylation PhosphoSitePlus
K1156 Ubiquitination PhosphoSitePlus
T1161 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S1163 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
T1165 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y1182 Phosphorylation PhosphoSitePlus
T1213 Phosphorylation PhosphoSitePlus
K1217 Ubiquitination PhosphoSitePlus   UniProt 22358839
Site PTM Type PTM Enzyme Score Source PMID
Y331 Phosphorylation HPRD 20068231
S337 Phosphorylation HPRD 20068231
T338 Phosphorylation HPRD 20068231
S350 Phosphorylation HPRD 20068231
S521 Phosphorylation HPRD 17081983
S527 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18707149
S532 Phosphorylation HPRD 17081983
S799 Phosphorylation HPRD 17081983, 18767875, 18452278, ...19651622, 18669648, 18707149, 20166139, 20068231
Y804 Phosphorylation HPRD 19651622, 17081983, 20068231
T1121 Phosphorylation HPRD 20068231
T1122 Phosphorylation HPRD 20068231
T1161 Phosphorylation HPRD 17081983, 20068231
S1163 Phosphorylation HPRD 19651622, 18767875, 18669648, ...20068231
T1165 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
Y331 Phosphorylation HPRD 20068231
S337 Phosphorylation HPRD 20068231
T338 Phosphorylation HPRD 20068231
S350 Phosphorylation HPRD 20068231
S521 Phosphorylation HPRD 17081983
S527 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18707149
S532 Phosphorylation HPRD 17081983
S799 Phosphorylation HPRD 17081983, 18767875, 18452278, ...19651622, 18669648, 18707149, 20166139, 20068231
Y804 Phosphorylation HPRD 19651622, 17081983, 20068231
T1106 Phosphorylation HPRD 20068231
T1107 Phosphorylation HPRD 20068231
T1146 Phosphorylation HPRD 17081983, 20068231
S1148 Phosphorylation HPRD 19651622, 18767875, 18669648, ...20068231
T1150 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
Y331 Phosphorylation HPRD 20068231
S337 Phosphorylation HPRD 20068231
T338 Phosphorylation HPRD 20068231
S350 Phosphorylation HPRD 20068231
S521 Phosphorylation HPRD 17081983
S527 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18707149
S532 Phosphorylation HPRD 17081983
S799 Phosphorylation HPRD 17081983, 18767875, 18452278, ...19651622, 18669648, 18707149, 20166139, 20068231
Y804 Phosphorylation HPRD 19651622, 17081983, 20068231
T1007 Phosphorylation HPRD 20068231
T1008 Phosphorylation HPRD 20068231
T1047 Phosphorylation HPRD 17081983, 20068231
S1049 Phosphorylation HPRD 19651622, 18767875, 18669648, ...20068231
T1051 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
Y331 Phosphorylation HPRD 20068231
S337 Phosphorylation HPRD 20068231
T338 Phosphorylation HPRD 20068231
S350 Phosphorylation HPRD 20068231
S760 Phosphorylation HPRD 17081983, 18767875, 18452278, ...19651622, 18669648, 18707149, 20166139, 20068231
Y765 Phosphorylation HPRD 19651622, 17081983, 20068231
T1082 Phosphorylation HPRD 20068231
T1083 Phosphorylation HPRD 20068231
T1122 Phosphorylation HPRD 17081983, 20068231
S1124 Phosphorylation HPRD 19651622, 18767875, 18669648, ...20068231
T1126 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
T10 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T122 A122 Biomuta DOID:1909 / melanoma [ cosmic ]
T122 I122 Biomuta DOID:363 / uterine cancer [ tcga ]
R486 H486 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R486 L486 Biomuta DOID:1324 / lung cancer [ tcga ]
S532 R532 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S557 Y557 Biomuta DOID:3571 / liver cancer [ icgc ]
K707 Q707 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R894 Q894 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R894 * Biomuta DOID:363 / uterine cancer [ tcga ]
T1121 N1121 Biomuta DOID:3571 / liver cancer [ icgc ]
K1156 E1156 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S1163 L1163 Biomuta DOID:4362 / cervical cancer [ cosmic, tcga ] DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]