iPTMnet Report for O94973 (AP2A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94973 / AP2A2_HUMAN
Protein Name AP-2 complex subunit alpha-2
Gene Name Name: AP2A2
Synonyms:ADTAB,CLAPA2,HIP9,HYPJ,KIAA0899;
Organism Homo sapiens (Human)

PRO ID PR:O94973
DAG View
PRO Name AP-2 complex subunit alpha-2 (human)
Definition An AP-2 complex subunit alpha-2 that is encoded in the genome of human.
Short Label hAP2A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94973 (AP2A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
R21 Methylation PhosphoSitePlus
C23 Methylation IEDB 31844290
K35 Acetylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
Y455 Phosphorylation PhosphoSitePlus
T536 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
R569 Methylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
K619 Ubiquitination PhosphoSitePlus
T623 Phosphorylation PhosphoSitePlus
T625 Phosphorylation PhosphoSitePlus
T630 Phosphorylation PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
K712 Ubiquitination PhosphoSitePlus
K842 Ubiquitination PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S231 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T623 M623 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]