iPTMnet Report for O94966 (USP19)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94966 / UBP19_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 19
Gene Name Name: USP19
Synonyms:KIAA0891,ZMYND9;
Organism Homo sapiens (Human)

PRO ID PR:O94966
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 19 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 19 that is encoded in the genome of human.
Short Label hUSP19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94966 (USP19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation IEDB   PhosphoSitePlus 32387766
S22 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
Y47 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
T91 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
C152 Methylation IEDB 31844290
S183 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
S244 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163
Y302 Phosphorylation PhosphoSitePlus
T407 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T446 Phosphorylation PhosphoSitePlus
T452 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K735 Ubiquitination PhosphoSitePlus
C817 Methylation IEDB 31844290
K823 Ubiquitination PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus
K1092 Ubiquitination PhosphoSitePlus
K1120 Ubiquitination PhosphoSitePlus
K1136 Ubiquitination PhosphoSitePlus
S1242 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
Site PTM Type PTM Enzyme Score Source PMID
S244 Phosphorylation HPRD 15302935, 20068231
S406 Phosphorylation HPRD 20068231
T407 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T407 Phosphorylation PhosphoSitePlus
Y1274 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S215 Phosphorylation PhosphoSitePlus
R241 Methylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S244 F244 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S406 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T446 S446 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T452 N452 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K610 T610 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K651 R651 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
C817 F817 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1092 M1092 Biomuta DOID:1319 / brain cancer [ cosmic ]
K1136 M1136 Biomuta DOID:1324 / lung cancer [ cosmic ]