iPTMnet Report for O94923 (GLCE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94923 / GLCE_HUMAN
Protein Name D-glucuronyl C5-epimerase
Gene Name Name: GLCE
Synonyms:KIAA0836;
Organism Homo sapiens (Human)

PRO ID PR:O94923
DAG View
PRO Name D-glucuronyl C5-epimerase (human)
Definition A D-glucuronyl C5-epimerase that is encoded in the genome of human.
Short Label hGLCE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94923 (GLCE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S44 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K54 Acetylation PhosphoSitePlus
S59 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
S73 Phosphorylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
Y140 Phosphorylation PhosphoSitePlus
N225 N-Glycosylation GlyGen   UniProt 30872481, 19159218
N303 N-Glycosylation GlyGen   UniProt 30872481
K371 Acetylation PhosphoSitePlus
N393 N-Glycosylation GlyGen   UniProt 30872481
Y458 Phosphorylation HPRD   PhosphoSitePlus 18491316
Y538 Phosphorylation PhosphoSitePlus
Y560 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S44 I44 Biomuta DOID:263 / kidney cancer [ icgc ]
S59 F59 Biomuta DOID:1612 / breast cancer [ cosmic ]
K371 R371 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]