iPTMnet Report for O94901 (SUN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94901 / SUN1_HUMAN
Protein Name SUN domain-containing protein 1
Gene Name Name: SUN1
Synonyms:KIAA0810,UNC84A;
Organism Homo sapiens (Human)

PRO ID PR:O94901
DAG View
PRO Name SUN domain-containing protein 1 (human)
Definition A SUN domain-containing protein 1 that is encoded in the genome of human.
Short Label hSUN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94901 (SUN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation P06493 (CDK1) PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 25482198
S52 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
T77 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S82 Phosphorylation IEDB   PhosphoSitePlus 35494241
K84 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus   UniProt 20068231
S103 Phosphorylation PhosphoSitePlus
T112 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus   RLIMS-P 28831067
S114 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
S138 Phosphorylation P53350 (PLK1) phospho.ELM   PhosphoSitePlus   RLIMS-P+   Signor   UniProt 23186163, 17081983, 25482198, ...18669648, 24275569, 20068231
K159 Ubiquitination PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
D333 Phosphorylation UniProt 20068231
K340 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus   UniProt 23186163
K392 Ubiquitination PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
N561 N-Glycosylation GlyGen 24190977
K604 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
Y677 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
N705 N-Glycosylation GlyGen 24190977
Site PTM Type PTM Enzyme Score Source PMID
S209 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation HPRD 20068231
S88 Phosphorylation HPRD 18669648, 17081983, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S138 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O94901 (SUN1) S113 Q9UBU9 (NXF1) decreased_association eFIP 28831067


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S50 A50 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S79 G79 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S82 F82 Biomuta DOID:4159 / skin cancer [ cosmic ]
S100 A100 Biomuta DOID:9256 / colorectal cancer [ cosmic ]