iPTMnet Report for O94900 (TOX)
Protein Information
UniProt AC / UniProt ID | O94900 / TOX_HUMAN |
Protein Name | Thymocyte selection-associated high mobility group box protein TOX |
Gene Name | Name: TOX Synonyms:KIAA0808; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O94900 |
PRO Name | thymocyte selection-associated high mobility group box protein TOX (human) |
Definition | A thymocyte selection-associated high mobility group box protein TOX that is encoded in the genome of human. |
Short Label | hTOX |
Category | organism-gene |
O94900 (TOX) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R4 | Methylation | score1 | PhosphoSitePlus | |||
Y149 | Phosphorylation | score1 | PhosphoSitePlus | |||
S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
K245 | Acetylation | score1 | PhosphoSitePlus | |||
K246 | Acetylation | score1 | PhosphoSitePlus | |||
K252 | Acetylation | score1 | PhosphoSitePlus | |||
K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
K307 | Ubiquitination | score1 | PhosphoSitePlus | |||
K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
S336 | O-Glycosylation | score1 | GlyGen | 35132862, 28657654, 35254053 | ||
S336 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y337 | Phosphorylation | score1 | PhosphoSitePlus | |||
S338 | O-Glycosylation | score1 | GlyGen | 35132862, 28657654, 35254053 | ||
S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
K344 | Ubiquitination | score1 | PhosphoSitePlus | |||
S346 | O-Glycosylation | score1 | GlyGen | 35132862, 28657654, 35254053 | ||
Y492 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y511 | Phosphorylation | score1 | PhosphoSitePlus | |||
S513 | Phosphorylation | score1 | PhosphoSitePlus | |||
T526 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S216 | P216 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K245 | E245 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K246 | N246 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K280 | N280 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y337 | C337 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K344 | N344 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S513 | T513 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T526 | A526 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |