iPTMnet Report for O94898 (LRIG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94898 / LRIG2_HUMAN
Protein Name Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor
Gene Name Name: LRIG2
Synonyms:KIAA0806,LIG2;
Organism Homo sapiens (Human)

PRO ID PR:O94898
DAG View
PRO Name leucine-rich repeats and immunoglobulin-like domains protein 2 (human)
Definition A leucine-rich repeats and immunoglobulin-like domains protein 2 that is encoded in the genome of human.
Short Label hLRIG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94898 (LRIG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S163 Phosphorylation PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
N173 N-Glycosylation GlyGen 24190977
S175 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
N441 N-Glycosylation GlyGen 24190977
Y541 Phosphorylation PhosphoSitePlus
T545 Phosphorylation PhosphoSitePlus
T612 Phosphorylation PhosphoSitePlus
S697 Phosphorylation IEDB 32387766
T708 Phosphorylation PhosphoSitePlus
N728 N-Glycosylation GlyGen 24190977
Y906 Phosphorylation PhosphoSitePlus
Y912 Phosphorylation PhosphoSitePlus
Y918 Phosphorylation PhosphoSitePlus
Y923 Phosphorylation PhosphoSitePlus
S1062 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T612 A612 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y906 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y912 F912 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y923 C923 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1062 R1062 Biomuta DOID:2394 / ovarian cancer [ cosmic ]