iPTMnet Report for O94868 (FCHSD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94868 / FCSD2_HUMAN
Protein Name F-BAR and double SH3 domains protein 2
Gene Name Name: FCHSD2
Synonyms:KIAA0769,SH3MD3;
Organism Homo sapiens (Human)

PRO ID PR:O94868
DAG View
PRO Name F-BAR and double SH3 domains protein 2 (human)
Definition An F-BAR and double SH3 domains protein 2 that is encoded in the genome of human.
Short Label hFCHSD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94868 (FCHSD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K59 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
Y226 Phosphorylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
C474 Methylation IEDB 31844290
S532 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
S646 Phosphorylation PhosphoSitePlus
Y659 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
Y667 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y677 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus   UniProt 30249660, 23186163
S683 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
T703 Phosphorylation PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
Y708 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S175 Phosphorylation HPRD 20068231
S178 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K59 R59 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y226 H226 Biomuta DOID:1324 / lung cancer [ cosmic ]
S646 P646 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S674 R674 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S681 Y681 Biomuta [ cosmic ]
S688 N688 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S700 * Biomuta DOID:1324 / lung cancer [ cosmic ]