iPTMnet Report for O94856 (NFASC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94856 / NFASC_HUMAN
Protein Name Neurofascin precursor
Gene Name Name: NFASC
Synonyms:KIAA0756;
Organism Homo sapiens (Human)

PRO ID PR:O94856
DAG View
PRO Name neurofascin (human)
Definition A neurofascin that is encoded in the genome of human.
Short Label hNFASC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94856 (NFASC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K86 Acetylation PhosphoSitePlus
K86 Methylation PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
N305 N-Glycosylation GlyGen 29741879
N409 N-Glycosylation GlyGen   UniProt 21047790
Y445 Phosphorylation PhosphoSitePlus
N446 N-Glycosylation GlyGen 23090970, 29741879
N467 N-Glycosylation GlyGen 24497634
S471 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y481 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S485 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y565 Phosphorylation PhosphoSitePlus
N752 N-Glycosylation GlyGen 29741879
N778 N-Glycosylation GlyGen 29741879
N973 N-Glycosylation GlyGen 29741879
T975 O-Glycosylation GlyGen 28657654
N984 N-Glycosylation GlyGen 23090970, 29741879, 24190977
Y1319 Phosphorylation PRO
Site PTM Type PTM Enzyme Score Source PMID
T585 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S471 Phosphorylation HPRD 18669648
Y481 Phosphorylation HPRD 18669648
S485 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S482 Phosphorylation HPRD 18669648
Y492 Phosphorylation HPRD 18669648
S496 Phosphorylation HPRD 18669648
Y1141 Phosphorylation HPRD 12223548, 11719549, 9371782
Site PTM Type PTM Enzyme Score Source PMID
S471 Phosphorylation HPRD 18669648
Y481 Phosphorylation HPRD 18669648
S485 Phosphorylation HPRD 18669648


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048587 (hNFASC/SigPep-/Phos:1) pY1319 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S471 N471 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S482 N482 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, cosmic ]
Y1141 H1141 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y1141 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]