Protein Information

Cytoscape View


UniProt AC / UniProt ID O94855 / SC24D_HUMAN
Protein Name Protein transport protein Sec24D
Gene Name Name: SEC24D
Synonyms:KIAA0755;
Organism Homo sapiens (Human)

PRO ID PR:O94855
DAG View
PRO Name protein transport protein Sec24D (human)
Definition A protein transport protein Sec24D that is encoded in the genome of human.
Short Label hSEC24D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94855 (SEC24D) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S22 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus   UniProt 23186163
R278 Methylation PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
K795 Ubiquitination PhosphoSitePlus
K803 Ubiquitination PhosphoSitePlus
S826 Phosphorylation PhosphoSitePlus
S831 Phosphorylation PhosphoSitePlus
K851 Ubiquitination PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
T988 Phosphorylation PhosphoSitePlus
K991 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S831 Phosphorylation HPRD 18452278


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049187 (hSEC24D/PhosRes+) p PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q15437 (SEC23B) S186 O94855 (SEC24D) inhibited_association eFIP 30596474


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K471 T471 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K594 N594 Biomuta DOID:363 / uterine cancer [ tcga ]
K851 T851 Biomuta DOID:1909 / melanoma [ icgc, tcga ]