iPTMnet Report for O94844 (RHOBTB1)
Protein Information
| UniProt AC / UniProt ID | O94844 / RHBT1_HUMAN |
| Protein Name | Rho-related BTB domain-containing protein 1 |
| Gene Name | Name: RHOBTB1 Synonyms:KIAA0740; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O94844 |
| PRO Name | Rho-related BTB domain-containing protein 1 (human) |
| Definition | A Rho-related BTB domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hRHOBTB1 |
| Category | organism-gene |
DAG ViewO94844 (RHOBTB1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S69 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31431478 | ||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T398 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31431478 | ||
| S480 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P | 17287340, 31431478 | ||
| T483 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P | 17287340, 31431478 | ||
| S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y542 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y544 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K679 | Ubiquitination | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | O94844 (RHOBTB1) | T398 | Q13618 (CUL3) | increased_association | eFIP | 31431478 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T483 | M483 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] | |
| S485 | L485 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
| Y544 | C544 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
