iPTMnet Report for O94830 (DDHD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94830 / DDHD2_HUMAN
Protein Name Phospholipase DDHD2
Gene Name Name: DDHD2
Synonyms:KIAA0725,SAMWD1;
Organism Homo sapiens (Human)

PRO ID PR:O94830
DAG View
PRO Name phospholipase DDHD2 (human)
Definition A phospholipase DDHD2 that is encoded in the genome of human.
Short Label hDDHD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94830 (DDHD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K53 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
Y128 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus
K254 Methylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
Y480 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
K587 Methylation PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus
K599 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S593 Phosphorylation HPRD 18212344


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K75 E75 Biomuta DOID:4159 / skin cancer [ cosmic ]
S129 P129 Biomuta DOID:1324 / lung cancer [ cosmic ]
S183 L183 Biomuta DOID:1612 / breast cancer [ cosmic ]
T184 A184 Biomuta DOID:1319 / brain cancer [ cosmic ]
T186 M186 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S373 I373 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]