iPTMnet Report for O94808 (GFPT2)
Protein Information
UniProt AC / UniProt ID | O94808 / GFPT2_HUMAN |
Protein Name | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 |
Gene Name | Name: GFPT2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O94808 |
PRO Name | glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (human) |
Definition | A glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 that is encoded in the genome of human. |
Short Label | hGFPT2 |
Category | organism-gene |
O94808 (GFPT2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K17 | Acetylation | score1 | PhosphoSitePlus | |||
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
T144 | Phosphorylation | score1 | PhosphoSitePlus | |||
S202 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 15133036 | ||
T227 | Phosphorylation | score1 | PhosphoSitePlus | |||
S244 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18767875, 18669648, 23186163 | ||
S245 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18767875, 17081983 | ||
K254 | Acetylation | score1 | PhosphoSitePlus | |||
K328 | Ubiquitination | score1 | PhosphoSitePlus | |||
C375 | Methylation | score1 | IEDB | 31844290 | ||
T444 | Phosphorylation | score1 | PhosphoSitePlus | |||
C461 | Methylation | score1 | IEDB | 31844290 | ||
K602 | Ubiquitination | score1 | PhosphoSitePlus | |||
S622 | Phosphorylation | score1 | PhosphoSitePlus | |||
K630 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y667 | Phosphorylation | score1 | PhosphoSitePlus | |||
K677 | Ubiquitination | score1 | PhosphoSitePlus | |||
S678 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S202 | I202 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S202 | R202 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S244 | I244 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y667 | D667 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S678 | Y678 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |