iPTMnet Report for O94788 (ALDH1A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O94788 / AL1A2_HUMAN
Protein Name Retinal dehydrogenase 2
Gene Name Name: ALDH1A2
Synonyms:RALDH2;
Organism Homo sapiens (Human)

PRO ID PR:O94788
DAG View
PRO Name retinal dehydrogenase 2 (human)
Definition A retinal dehydrogenase 2 that is encoded in the genome of human.
Short Label hALDH1A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O94788 (ALDH1A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus   UniProt 23186163
T170 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus   UniProt 23186163
K365 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K384 Acetylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K390 Acetylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 L22 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T170 S170 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K365 N365 Biomuta DOID:363 / uterine cancer [ cosmic ]
K370 N370 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K415 N415 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K512 N512 Biomuta DOID:1324 / lung cancer [ cosmic ]